Indica Labs Team and Collaborators

#2677  Sequential same slide multiplex immunofluorescence and H&E staining for combined phenotypic and morphologic characterization of formalin-fixed paraffin-embedded tissue sections
Katir K. Patel, Amanda Bares, Mael Manesse, Mark Burton, Bonnie Phillips, Kate Lillard, Anne Hellebust, Melinda Duplessis, Kyla Teplitz, Tad George. Ultivue, Inc., Cambridge, MA, Indica Labs, Albuquerque, NM, RareCyte, Seattle, WA

#4989  Introduction of a robust workflow for the whole-side acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay
Anne E. Hellebust, Kyla Teplitz, Katir K. Patel, Karan Sharma, Amanda Bares, Mael Manesse, Mark Burton, Bonnie Phillips, Sean Downing, Kate Lillard. Indica Labs, Inc., Albuquerque, NM, RareCyte, Inc., Seattle, WA, Ultivue, Inc., Cambridge, MA 

#LB-368  Applications of automated image analysis, machine learning and spatial statistics for the improvement of stage II colorectal cancer prognosis
Ines P. Nearchou, Daniel A. Soutar, Kate Lillard, Ueno Hideki, Ognjen Arandjelović, David J. Harrison, Peter D. Caie. University of St Andrews, St Andrews, United Kingdom, Indica Labs, Inc., Corrales, NM, National Defense Medical College, Saitama, Japan 

Customer Posters 

#LB-275  Measuring concordance of CD8 and PD-L1 expression in non-small cell lung cancer between a novel multiplex immunofluorescence assay and a brightfield laboratory developed test
Shravani Shitole, Monique Johnson, Courtney Hebert, Jamie Buell, Amy Ly, Sean R. Downing. Ultivue, Cambridge, MA, Mass General Hospital, Cambridge, MA 

#386   Design and application of an 8-plex multiplex immunofluorescence panel for deep phenotypic profiling of the tumor microenvironment using InSituPlex technology
Alexis Wong, Mara Koerner, Katir K. Patel, Anna Potier, Stephanie Hennek, Mustapha Abubakar, Mary E. Olanich, Yelena G. Golubeva, Karun Mutreja, Scott Lawrence. Ultivue, Inc., Cambridge, MA, National Cancer Institute, Rockville, MD, Frederick National Laboratory for Cancer Research, Frederick, MD 

#855   Spatial analytics of the tumor microenvironment on double stained immunohistochemistry images using deep learning
Mate L. Nagy, Anna Juncker-Jensen, Harry Nunns, Ben Ovadia, Ainura Kyshtoobayeva, Karen Yamamoto, Qingyan Au, Josette William Ragheb. NeoGenomics, Aliso Viejo, CA 

#1448  Cell DIVE™: A robust and standardized platform for multiplexed whole slide imaging and single cell analysis
Alex Corwin, Elizabeth McDonough, Christine Surrette, Prashanth Dumpuri, Anup Sood, Fiona M. Ginty. GE Global Research, Niskayuna, NY, GE Healthcare, Issaquah, NY 

#2143  Profiling exhausted T cells using Vectra® Polaris™multiplex immunofluorescence assay in HNSCC
Sara Pollan, Arezoo Hanifi, Mate Nagy, Nicholas Stavrou, Erinn Parnell, Maricel Gozo, Nickolas Attanasio, Josette William, Qingyan Au. NeoGenomics, CA 

#2637  Multiplex immunohistochemistry, spatial analysis, and gene expression profiling of the tumor-immune microenvironment in HNSCC tumors
Carlee Hemphill, Timothy Maynor, John Bauman, Caitlin Schroyer, Jeffery Shuster, Thomas Turi, Steven M. Anderson. Covance, Durham, NC 

#2679  Immuno-oncology panel optimization for imaging mass cytometry and digital image analysis of tumor tissues
Pedro Rocha, Luisa Solis, Edwin Parra, Ou Shi, Barbara Mino, Vidya C. Sinha, Amanda Rinkenbaugh, Auriole Tamegnon, Mak Duncan, Wei Lu, Mei Jiang, Lakshimi Kakarala, Jared K. Burks, Helen Piwnica-Worms, Cara Haymacker, Michael Teztlaff, Ignacio Wistuba, Alejandro Francisco-Cruz. MDAnderson Cancer Center, Houston, TX, MDAnderson Cancer Center, Houston, TX, MDAnderson Cancer Center, Houston, TX, MDAnderson Cancer Center, Houston, TX 

#2798  Cancer stem cells profiling of the colorectal cancer patient-derived xenograft model and corresponding in vitro organoid model by multiplex IHC
Xiaolong Tu, Xiaoyu An, Xiaoxi Xu, Xinhe Feng, Chen Jiang, Jared Allan Gunn, Henry Li. Crown Bioscience Inc, Taicang, China, Crown Bioscience Inc, Beijing, China, Crown Bioscience Inc, San

#3863  CODEX high-multiplex imaging reveals distinct tumor microenvironment in mouse melanoma models associated with response to immunotherapy
Noemi Kedei, Eva E. Pérez-Guijarro, Jin-Qiu Chen, Chi-Ping Day, Mariam Q. Malik, David J. Goldstein, Glenn T. Merlino. National Cancer Institute, Bethesda, MD, National Cancer Institute, Bethesda, MD, National Cancer Institute, Bethesda, MD, National Cancer Institute, Bethesda, MD 

#3873  High-multiplex automated staining and scanning workflow with Ultivue InSituPlex technology and the Olympus SLIDEVIEW VS200 slide scanner
Amanda J. Bares, Alec De Grand, Maël Manesse. Ultivue, Inc, Cambridge, MA, Olympus America Inc., Waltham, MA 

#4248  Multispectral immunofluorescence identifies pS6 as a biomarker of intrinsic resistance to ruxolitinib in patients with relapsed/refractory T-cell lymphomas
Paola Ghione, Alison Moskowitz, Priadarshini Kumar, Andrea Knezevic, Venkatraman Seshan, Eric Jacobsen, Jia Ruan, Johnathan Schatz, Sarah Noor, Patricia Myskowski, Helen Hancock, Theresa Davey, Obadi Obadi, Carlissa Onwasigwe, Nivetha Ganesan, Lauren Pomerantz, Christine Jarjies, Allison Sigler, Mark Geyer, Ariela Noy, David Straus, Natasha Galasso, Giorgio Inghirami, Steven Horwitz, David Weinstock, Travis Hollmann, Ahmet Dogan. Memorial Sloan Kettering Cancer Center, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, Dana Farber Cancer Institute, Boston, MA, Weill Cornell Medical College, New York, NY, University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL, Memorial Sloan Kettering Cancer Center, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY, Weill Cornell Medical College, New York, NY, Memorial Sloan Kettering Cancer Center, New York, NY 

#4317  Prognostic significance of SIRPa+ macrophages in esophageal squamous cell carcinoma
Yida Li, Li Chu, Xi Yang, Xiao Chu, Jianjiao Ni, Zhengfei Zhu. Fudan University Shanghai Cancer Center, China

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