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Masterclass Webinar 2: Advanced Techniques and Workflows for Multiplex IHC Analysis using HALO® and HALO AI

25 May 2023 | Following up on our Masterclass Webinar 1 for Multiplex IHC analysis, Masterclass 2 will discuss advanced workflows to help users tackle more challenging brightfield multiplex IHC assays. First, we will demonstrate how advanced cell segmentation and phenotyping options using HALO AI can be combined with the multiplex IHC module to improve image analysis. Two alternative approaches for analyzing multiplex IHC will also be demonstrated including a serial stain workflow to convert brightfield images into...

Getting Started with RNAscope™ Image Analysis in HALO®

28 March 2023 | Join us for this 1-hour webinar to see a live demonstration of RNAscope image analysis using the HALO® platform from Indica Labs. This webinar will demonstrate the basic functionality of HALO’s RNAscope modules for analysis of brightfield and fluorescence images and will discuss available analysis outputs. In addition, select HALO modules that are commonly used with RNAscope image analysis will be demonstrated, and a brief introduction to how HALO AI can advance your RNAscope will be...

HALO AP® 2.1 Features and Functionalities

In this blog post, you can learn about the latest release of HALO AP®, a CE marked, AI powered and pathologist driven image management platform from Indica Labs. We’ll discuss the new features in HALO AP 2.1, where to find training resources and documentation, and how the upgrade will be rolled out. ...

Looking Back: Reviewing 2022 at Indica Labs

Reflecting over the last year, we at Indica Labs would like to express our gratitude to the customers and collaborators who helped fill 2022 with exciting discoveries, events, and partnerships. It is our honor to have played a part in customers’ contributions to scientific fields ranging from oncology to infectious disease, immunology, neurology, and biomaterials. ...

Press Release: Indica Labs and Hamamatsu Photonics K.K. Announce Collaboration to Provide Optimized Integrated Digital Pathology Workflows

Albuquerque, NM and Hamamatsu City, Japan, - 14th October 2022 - Indica Labs, an industry leader in quantitative digital pathology and image management solutions, and Hamamatsu Photonics K.K., a forerunner in whole slide imaging systems, announced an agreement to maintain long-term interoperability between Indica Labs’ HALO AP® software platform and Hamamatsu’s NanoZoomer family of high-speed, high-resolution scanners. ...

Press Release: Leica Biosystems Announces Partnership with Indica Labs to Deliver Integrated Digital Pathology Workflow Solutions for Mutual Customers

Vista, CA - Sep 4, 2022, Leica Biosystems, a cancer diagnostics company and a global leader in workflow solutions, and Indica Labs, the industry-leading provider of computational and image management software in digital pathology, today announced a partnership focused on delivering compatible digital pathology workflow solutions. ...

Press Release: Indica Labs Announces Collaboration with The Industrial Centre for Artificial Intelligence Research in Digital Diagnostics (iCAIRD) for the Development of an AI-based Algorithm for the Automated Reporting of Lymph Node Status in Colon Cancer

Albuquerque, NM, and Glasgow, Scotland, – 30 August, 2022 – Indica Labs, an industry leader in quantitative digital pathology and image management solutions, and The Industrial Centre for Artificial Intelligence Research in Digital Diagnostics (iCAIRD), announced today an agreement to collaborate on the development of an AI-based digital pathology solution for the detection of cancer within lymph nodes from colorectal surgery cases....

Press Release: Deep Bio successfully integrates DeepDx® Prostate algorithm into HALO AP® platform from Indica Labs

Seoul, South Korea, and Albuquerque, NM – August 9, 2022 – Deep Bio, a company concentrating on SaMD (Software as a Medical Device) for digital pathology, is offering clinically validated, AI-based DeepDx® algorithms, and Indica Labs, a leading provider of computational pathology software and services, are excited to announce the successful integration of the DeepDx® Prostate algorithm into the HALO AP® platform from Indica Labs. ...

Press Release: Indica Labs receives top honor in Albuquerque Journal ‘Flying 40’ list of top tech firms in New Mexico

Albuquerque, NM, 13 June, 2022 – Indica Labs, a leading provider of computational pathology software and services is proud to announce today they have received the top award in the Albuquerque Journal ‘Flying 40’ analysis of technology firms in New Mexico. Indica Labs participated in the Flying 40 for the first time in 2022 and received the top honor based on a 323% increase in revenue over the past 5 years. In that same time period, the number of employees...

Press Release: Indica Labs achieves CE-IVD certification for AI-based Prostate Cancer Detection and Gleason Grading Tool

ALBUQUERQUE, NM – May 24, 2022 – Indica Labs, the leading provider of computational pathology software and services, is excited to announce a CE-IVD Mark for HALO Prostate AI, a deep learning-based screening tool designed to assist pathologists in identifying and grading prostate cancer in core needle biopsies....

Press Release: Lunaphore and Indica Labs announce partnership to provide complete technology solution for spatial biology and image analysis

LAUSANNE, Switzerland and ALBUQUERQUE, N.M. – May 12, 2022 – 5 pm (CET) | 9 am MDT – Lunaphore, a Swiss life sciences company developing technology to enable spatial biology in every laboratory, and Indica Labs, a leading provider of computational pathology software and services, today announced a partnership to co-market an end-to-end solution that combines Lunaphore’s flagship COMET™ spatial biology platform and Indica’s HALO® and HALO AI™ digital pathology image analysis software....

HALO AP 2.0 Features and Functionalities

In this blog post, you can learn about the new features in HALO AP 2.0, the CE marked anatomic pathology case management software from Indica Labs, where to find training resources and documentation, and how the upgrade will be rolled out. ...

Interested in Quantitative Image Analysis in Oncology?

In this blog post, you can learn about what the team at Indica Labs has planned for the upcoming AACR 2022 conference in New Orleans! From April 10-13, our team will be in  booth #1147, and our Applications Scientists will be available to answer any questions you have about how our HALO® software suite can advance your oncology research and can provide you with a demonstration of the latest release of our flagship HALO® image analysis software, our powerful HALO AI™ deep learning add-on, and our HALO Link™ collaborative...

Announcing the Vacuole Quantification module v3.2

/*! elementor - v3.5.0 - 12-12-2021 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} We’re excited to announce the launch of the updated Vacuole Quantification module v3.2!  In this blog post, you can learn about some of the new features in this module, where to find the user guide and tutorial video, and when to expect to upgrade. /*! elementor - v3.5.0 - 12-12-2021 */.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px} What New Features are Included in the Module? This major module update includes the following features: ...

HALO AP 2.0 Sneak Peek

29 March 2022 | A new version of HALO AP, Indica Labs’ clinical case management software, is coming soon! HALO AP 2.0 reimagines the pathologist’s cockpit with an updated case viewer and several new workflow enhancements. In this hour-long webinar, we will demonstrate these new features and end with a Q&A session. ...

Optimizing quantitative analysis of highly multiplexed CODEX images in HALO

31 March 2022 | In this webinar, Dr. Noemi Kedei, a staff scientist at the Collaborative Protein Technology Resource core of the Center for Cancer Research (CCR) at the National Cancer Institute, will present a comprehensive CODEX workflow, from image acquisition to image processing and HALO image analysis. Dr. Kedei leads the core facility that provides this technology as service to CCR investigators, including project consultation and design, antibody panel customization, tissue staining and imaging, image processing, and...

RNAscope common questions, troubleshooting, and tips and tricks

When performing RNAscope image analysis, you can set yourself up for success with a combination of thoughtful experimental design, rigorous assay execution and validation. At Indica Labs, the most common challenges we see in RNAscope image analysis include chromogenic staining that has saturated to black, which causes color deconvolution challenges, loss of nuclear morphology due to over-digestion of tissue, and failing to verify and validate an image analysis solution before scaling up....

Bridge the Gap with Indica Labs’ Pharma Services

At Indica Labs, our Pharma Services team is here to help you extract more data from your biomarker assays with our digital image analysis services. From single biomarker IHC to ISH/FISH and highly multiplexed fluorescence and imaging mass cytometry, we offer quantitative image analysis solutions with our own HALO and HALO AI analysis platforms. With over 150 completed image analysis projects, our team has experience across multiple disease areas, applications, and assay types, including immune phenotyping in tumors, biomarker expression...

2021: A Year in Review at Indica Labs

As 2021 draws to a close, the team at Indica Labs would like to take this opportunity to reflect on the year and to thank our customers for their continued support through this second pandemic year. Despite the ongoing challenges that the pandemic presents, we celebrate the achievements of our customers who have published over 250 publications in peer-reviewed journals this year with an impressive average impact factor of 9.12. To learn more about these publications spanning immuno-oncology, oncology, immunology,...

A Deep Learning Convolutional Neural Network Can Differentiate Between Helicobacter Pylori Gastritis and Autoimmune Gastritis with Results Comparable to Gastrointestinal Pathologists

13 January 2022 | In this 60-minute webinar, researchers and pathologists from the University of New Mexico will discuss their recently published study using the HALO AI™ deep learning convolutional neural network (CNN) to determine whether a CNN can differentiate autoimmune gastritis from Helicobacter pylori gastritis....

Using digital pathology to determine the role of tumor-infiltrating B cells in clinical outcome of patients with melanoma

15 December 2021 | This webinar will share an analysis of biomarkers using pre-treatment melanoma samples from the dabrafenib plus trametinib arm of the randomized, Phase III COMBI-v trial using the HALO® image analysis platform combined with gene expression analysis using the Nanostring nCounter technology....

Automated detection and quantitation of gastric immune cells in a mouse model of Helicobacter pylori­-driven preneoplastic progression

21 October 2021 | Gastric cancer is the fourth-leading cause of cancer death worldwide. About 80% of cases are attributable to infection with the bacterium Helicobacter pylori (Hp). Untreated Hp infection causes lifelong stomach inflammation that does not eradicate the bacterium. In some individuals, stomach inflammation leads to preneoplastic progression, a series of sequential tissue changes including loss of gastric acid-producing parietal cells, metaplasia, dysplasia, and finally cancer....

CD38 in the Prostate Tumor Microenvironment

6 October 2021 | CD38, a druggable ectoenzyme, is involved in the generation of adenosine, which is implicated in tumor immune evasion. Its expression and role in prostate tumor-infiltrating immune cells (TIICs) have not been elucidated. We characterized CD38 expression on prostate cancer (PC) epithelial cells and TIICs and explored the association of this expression with clinical outcomes. RNAseq from 159 patients with metastatic castration-resistant prostate cancer (mCRPC) in the International Stand Up To Cancer/Prostate Cancer Foundation (SU2C/PCF) cohort and 171...

Press Release: Indica Labs earns Work/Life Flexibility award and is named a Top Workplace by The Albuquerque Journal for the second year running

Albuquerque, NM, 2 September, 2021 – Indica Labs, a leading provider of computational pathology software, is proud to announce that they have been awarded a Top Workplaces™ honor by The Albuquerque Journal for a second year in a row.  In addition to being a Top Workplace, Indica Labs was the sole recipient of the Life/Work Flexibility award for 2021....

An interview with Charles Habermehl, Software Engineer (Previous Intern)

Q1. As an intern, what projects were you assigned to work on? What skills did you acquire or improve while working on these projects? A1. As an intern I was assigned to work on the Halo Link team. Before working on the Halo Link team I had no experience in Web Development which is the main skill I picked up in my time here so far. To be specific, before I started I did not know JavaScript and am now quite...

An interview with Anas Gauba, Software Engineer (Previous Intern)

Q1. As an intern, what projects were you assigned to work on? What skills did you acquire or improve while working on these projects? A1. As an intern, I worked on the project to build quota-system where the customer can buy some quota whether it be quota for doing analysis, disk storage, etc. I also worked on building a loginAttempt feature where we can track important information such as customers’ ip address and which service they logged in from. The projects...

Automated Detection and Gleason Grading of Prostate Cancer in Digital Pathology

8 September 2021 | Digital pathology provides an advantage of automatizing many routine pathological tasks via computational algorithms and tools. The reporting of prostate cases is time-consuming due to a large number of slides per case. Moreover, tumor aggressivity grading (Gleason score) is well known for its subjective nature and high levels of interobserver variability. In this webinar, we will demonstrate a deep learning-based tool developed for the detection of prostate cancer in histological slides (prostate biopsies and prostatectomy...

Press Release: Nottingham University Hospitals NHS Trust selects Indica Labs to deliver their Digital Pathology Solution with HALO AP

Albuquerque, NM, USA and Nottingham, UK, 1 July, 2021 – Following a formal tender process, Nottingham University Hospitals (NUH) NHS Trust today announced the selection of Indica Labs to aid in full digitisation of the pathology workflow. Indica Labs will deliver its leading digital pathology software, HALO AP®, fully integrated with existing hospital systems, alongside multiple Hamamatsu Nanozoomer scanners....

Press Release: Indica Labs and Ibex Partner to Deliver AI-powered Clinical Workflows for Digital Pathology

ALBUQUERQUE, NM and TEL AVIV, Israel – May 20, 2021 – Indica Labs, an industry leader in quantitative digital pathology & image management solutions, and Ibex Medical Analytics, a pioneer in artificial intelligence (AI) based cancer diagnostics, announced an agreement to integrate the Galen™ AI-based cancer diagnostics platform into the HALO AP® digital pathology workflow platform....

Automated detection and classification of prognostic histopathological features in colorectal cancer using deep learning

9 June 2021 | Deep learning can be applied to both clinical and research based digital pathology. Doing so can bring multiple advantages to both fields. In this talk, Dr. Peter Caie and Dr. Ines Nearchou we will discuss these advantages and describe a specific proof of principle that applies AI to the quantification of an important histopathological feature in colorectal cancer, desmoplastic reaction (DR)....

Approaches to Analyzing Skin Tissue using HALO and HALO AI

6 May 2021 | Application Scientist, Natasha Carmell, will discuss and demonstrate workflow approaches for analysing skin sections stained with H&E and immunofluorescence. Using HALO AI we will identify and segment the corneal layer, epidermis, dermis, cartilage, sebaceous glands and lesions in H&E murine auricular tissues, followed by the segmentation of carcinoma from melanoma in fluorescent multiplexed Melanoma tissue. This AI based tissue segmentation will then be combined with biomarker quantification to identify CD8, CD68 and PDL1 positive populations using...

Tips & Tricks: Batch Processing Productivity Tools

29 April 2021 | Batch processing workflows can be a significant time saver for HALO image analysis. In this masterclass, US Application Scientist Michael Tomac will cover six different batch process workflows available in HALO, including: - Registration, including batch registration of TMAs - Annotation Editing & Deletion - Analysis - Edit Result Layers - Spatial Analysis from scratch and using saved settings - View Settings - Export Michael will also highlight changes in batch workflows introduced in HALO 3.3, so this is a great opportunity for HALO...

HistoTalks: NSH Podcasts

Check out the latest National Society for Histotechnology HistoHelp podcast with Dave Krull and Adam Smith! In Part 1 of the HistoHelp AI in the Lab podcast, David Krull, the NSH podcast expert and AI advocate, talks to Adam Smith, Director of Life Science Applications at Indica Labs, about approaches to implement and validate AI in the lab. Click the tab below to listen and learn a little bit about how to train AI algorithms! In Part 2 of the HistoHelp AI in...

Comparison of stain co-localization in IHC sequential cuts and true co-expression in mIF images from Polaris

8 April 2021 | The webinar will cover a workflow for performing stain co-localization analysis in sequential IHC cuts through color deconvolution, slide registration, and cell-type classification, including export using registered coordinates. The resulting co-localization output will be compared and contrasted to true co-expression on a single slide using mIF techniques (Polaris)....

HALO Image Analysis Masterclass Series: Indica Labs Tech Toolbox Webinar

1 April 2021 | The Indica Labs software products have a number of additional tools to extend the utility of our products beyond the HALO user interface most users are familiar with. These tools allow users to query the underlying database for metadata imported to HALO Link, integrate with LIMS, plugin convolutional neural networks not available in HALO, write analysis modules from scratch, and more....

Webinar: Using the HALO image analysis platform to study pancreas pathology and insulitis in young people with recent-onset Type 1 diabetes

4 March 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT Type 1 diabetes is an autoimmune condition leading to the T-cell mediated destruction of insulin-containing beta cells. Worldwide, fewer than 600 Type 1 diabetes pancreata have been described in the literature or are accessible within tissue biobanks. Due to welcome improvements in the diagnosis and clinical management of Type 1 diabetes, deaths close to diagnosis are now very rare in young...

HALO Image Analysis Masterclass Series: February-March 2021

February 2021 | Indica Labs is excited to continue our HALO® Masterclass Webinar Series this winter. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide.These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher...

Webinar | HALO® Image Analysis Masterclass Series: Object-based Analysis

28 January 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT | Looking for an easy way to quantify plaques or vessels in your images? Register for our next masterclass! In the first of our 2021 Masterclass series, East Coast Application Scientist Alyssa Myers will discuss object-based analysis. Using HALO, this masterclass will provide an in-depth look at our brightfield and fluorescent object colocalization analysis modules....

Webinar | Digital Pathology in the New Normal: Leveraging HALO® to Investigate a Global Pandemic

21 January 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT | As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the...

Message from our CEO

Dear friends of Indica Labs, I’d like to take a moment to share some updates and to thank each and every person that has supported Indica through the exceptional challenges of 2020. While the world struggles with a viral pandemic, the importance of digital pathology has never been clearer. Indica’s products are utilized by every pharmaceutical company that’s been in the news recently for their COVID-19 vaccine and therapeutic production. In a matter of weeks after the start of the pandemic, our...

Upcoming Presentation | Integrated Workflow and AI: Realizing the benefits in clinical digital pathology, by Katie McKinley, Head of Clinical Sales – Europe

December 3, 2020 12:30 - 1:00 GMT In this session we will look at how AI can provide time savings, increased accuracy, and offer an enhanced experience for the pathologist. We will also discuss the some of the key considerations when implementing AI. HALO AP integrates AI and analysis directly into the workflow, while at the same time offering a wide range of tools for anywhere, anytime access to digital slides for busy clinical pathology labs....

Upcoming Presentation | HALO AP: An Integrated Clinical workflow for Qualitative and Quantitative Pathology, by Katie McKinley, Head of Clinical Sales – Europe

November 24, 2020 12:20 CET ESDIP presents their first-ever workshop - Going into digital pathology in pandemic times: all you need to know for implementation. This online, one- track event primarily serves to help those who wish to start a digital workflow in their pathology laboratories of pathology, with the presentation of models of successful implementation. Don't miss Ms. McKinley's presentation on HALO AP and our integrated workflow....

HALO AP 1.1 – Streamlining Clinical Workflows

November 12, 2020 8:00 PST | 11:00 EST | 16:00 GMT The next release of HALO AP, Indica Lab’s state-of-the-art anatomic pathology software, will be available soon. Join us to see how HALO AP provides anywhere, anytime access to digital slides for remote sign-out, secondary consultations, tumor board management as well as quantitative IHC, and get a first look at the latest new features....

Press Release: Indica Labs announce integration of Philips iSyntax image format across all HALO® software platforms

Albuquerque, NM– October 22, 2020 – Indica Labs, a leading provider of computational pathology software and services, is pleased to announce integration of the Philips iSyntax image format into the full range of HALO® software platforms. This includes HALO AP for case-based image management and quantitative workflows, HALO Link for research image management and collaboration, HALO for image analysis, and HALO AI for AI-based tissue classification....

Press Release: Indica Labs announces launch of enterprise-wide, cloud-based digital pathology deployment at NCI

Albuquerque, NM – October 8, 2020 – Indica Labs, a leading provider of computational pathology software and services, are pleased to announce the formal launch of an enterprise-wide, cloud-based deployment of Indica Labs’ software within the National Cancer Institute (NCI), including HALO®, HALO AI, HALO Link and HALO AP. Accessible to hundreds of users within the NCI, managing millions of digital images, and facilitating the analysis of thousands of images daily, this is the largest single deployment of Indica Labs’...

Collaborating with HALO Link

8 October, 2020 8:00 PDT | 11:00 EDT | 16:00 BST HALO Link offers a variety of tools to involve collaborators in your image analysis projects. Join Jamie Lanctot, our HALO Link Product Specialist, to explore our latest workflows for connecting, collecting, organizing, and sharing data across accounts....

Digital Pathology in the New Normal: Leveraging HALO to Investigate a Global Pandemic

26 October 2020 11:00 – 12:35 PT As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the disease are critical to guiding treatment and influencing outcomes. Researchers around the world utilized...

HALO® MASTERCLASS WEBINAR SERIES

Indica Labs is excited to continue our HALO® Masterclass Webinar Series this autumn. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide. These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher training or additional...

INDICA LABS’ PHARMA SERVICES: FACILITATING TISSUE BASED IMMUNO-ONCOLOGY RESEARCH

15 October 2020, 9:30 PDT | 12:30 EDT | 17:30 BST In this 30 minute presentation, Jeff Dzubay, Ph.D. will present on the following topics:  - Immuno-Oncology biomarker assays benefit from high-plex technologies to better understand the immune landscape. - There are multiple workflows for multiplex IHC/IF assays. - HALO® is a comprehensive, easy-to-use, image analysis platform for analyzing multiplex assays to understand the immune profile within the spatial context of the tumor microenvironment. - The Pharma Services group at Indica Labs uses the HALO®...