Detect and measure axons and myelin areas with the HALO® Axon Quantification module. For use on brightfield images of stained nerve cross sections, this module reports the inner, outer, and myelin areas, inner and outer diameters, and G-Ratio for each axon, and provides both summary and detailed per-axon metrics. See the big picture and quickly spot outliers thanks to the module’s automatically generated histograms of axon G-Ratios and inner and outer diameters.
Try it out! Click here to initiate your free proof-of-concept HALO image analysis.
File formats supported by the HALO image analysis platform:
- Non-proprietary (JPG, TIF, OME.TIFF)
- Nikon (ND2)
- 3D Histech (MRXS)
- Akoya (QPTIFF, component TIFF)
- Olympus / Evident (VSI)
- Hamamatsu (NDPI, NDPIS)
- Aperio (SVS, AFI)
- Zeiss (CZI)
- Leica (SCN, LIF)
- Ventana (BIF)
- Philips (iSyntax, i2Syntax)
- KFBIO (KFB, KFBF)
- DICOM (DCM*)
*whole-slide images

HALO® Analysis Applications in Neuroscience Research
15 August 2018 | In this one hour webinar, Indica Labs’ Application Scientist, Alyssa Myers, will discuss how the HALO platform can be used for
Publication Spotlight
The table below includes publications that cite the Axon Quantification module.
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Title | Authors | Year | Journal | Application | HALO Modules |
---|---|---|---|---|---|
Intrathecal Administration of AAV/GALC Vectors in 10- 11-Day-Old Twitcher Mice Improves Survival and Is Enhanced by Bone Marrow Transplant | Karmuthil-Melethil S, Marshall MS, Heindel C, Jakubauskas B, Bongarzone ER, Gray SJ | 2016 | Journal of Neuroscience Research | Neuroscience | Axon |
Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury | Stewart A, Glaser E, Mott C, Bailey W, Sullivan P, Patel S, Gensel J | 2022 | Journal of Neurotrauma | Neuroscience | Axon |
Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions | Elbaz B, Yang L, Vardy M, Isaac S, Rader B, Kawaguchi R, Traka M, Woolf C, Renthal W, Popko B | 2022 | Cell Reports | Neuroscience | Axon |
Combination of pathological, biochemical and behavioral evaluations for peripheral neurotoxicity assessment in isoniazid-treated rats | Kashimura A, Nishikawa S, Ozawa Y, Hibino Y, Tateoka T, Mizukawa M, Nishina H, Sakairi T, Shiga T, Aihara N, Kamiie J | 2023 | Journal of Toxicologic Pathology | Toxicology | Axon |
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