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Area Quantification Tag

Indica Labs / Posts tagged "Area Quantification"

Transmission of tauopathy strains is independent of their isoform composition

Zhuohao He, et al, Nature Communications, 2020
The accumulation of aggregated tao proteins in neurons is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease. A challenge in the study of tauopathies has been the lack of an appropriate model system. He and colleagues demonstrate here a new mouse model for human tauopathies where the expression of tao isoforms is similar to that in human adult brains. The Area Quantification Module of HALO played a key role in the analysis...

Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters

Lisa H Tostanoski, et al, Nature Medicine, 2020
In this study led by researchers at Harvard Medical School, they report the first demonstration of prevention of severe clinical disease in a hamster model of SARS-CoV-2 that were provided with a single immunization of the adenovirus serotype 26 (Ad26) vaccine. The Ad26 vaccine utilizes a stabilized spike protein of the SARS-CoV-2 and in the United States this vaccine is commonly known as the Johnson and Johnson vaccine. This study,...