HALO AP 2.5: Scaling Digital Pathology with Intelligent Workflow Orchestration

In this blog post, we’ll discuss some of the exciting new features and functionalities in the latest release of HALO AP®, the CE-IVDR marked, AI-powered enterprise digital pathology platform from Indica Labs. We will also provide information about when you can expect your chance to upgrade to HALO AP® 2.5, as well as where to find user guides and release notes.

The 2.5 Release Collectively Advances:

  • Workflow Automation & Orchestration (Lab Logic)
  • Compliant and Audit-ready Traceability (Refined Flow)
  • Multi-site Collaboration (Tumor Board, Secondary Assignees)
  • Operational Scalability (Smart Slide Lists)
  • User Efficiency and System Transparency 

Lab Logic: Your Lab’s Logic, Built In.

Lab Logic includes an intelligent, configurable orchestration layer across the entire diagnostic workflow, transforming digital pathology from a collection of point solutions into a scalable workflow engine.

Users with a Flow Designer role can configure automated workflows by combining:

  • Manual steps
  • AI-driven triggers
  • Routing rules
  • Post-analysis automation
 

How this improves your workflow: Lab Logic automates AI-powered slide and case triage to ensure that every case has the right flow assignment and is sent to the proper work list.

Cancer care with collaboration in mind. The new and improved Tumor Board

This image shows the HALO AP 2.5 user interface, show casing tumor board 2.0 for multidisciplinary collaboration in diagnostics

Simplify complex case assembly and meeting management with smart tools like stain-based filtering and real-time slide additions, ensuring your original data stays pristine while your team stays synchronized.

  • Assign and schedule meetings, including recurring sessions
  • Share access with designated users or groups
  • Capture preparation notes and live discussion content
  • Add slides in real time without modifying original annotations

Additional features:

  • Drag-and-drop organization of discussion order
  • Rapid slide curation from case grids
  • Optional stain-based filtering for efficient case assembly
 

How this improves your workflow: A redesigned tumor board workspace enables efficient coordination across multidisciplinary teams ensuring comprehensive patient case evaluation. Shown here is stain-based filtering which significantly improves tumor boards by making it faster and easier for multidisciplinary teams to locate, review, and compare the most relevant pathology slides during case discussions.

Boost operational efficiency with smart slide lists and profiles

Users can create dynamic slide lists using filterable criteria such as:

  • Scanner
  • Stain
  • File location
  • Slide tags
 

How this improves your workflow: Lists can be saved to user profiles and assigned to specific users or groups, ensuring relevant data visibility across sites while reducing manual sorting and operational complexity.

Secondary Assignment Workflows

Supports collaborative review by allowing:

  • Multiple secondary reviewers
  • Structured review workflows
  • Automated notifications back to the primary pathologist

On-the-Fly Registration

Uses AI to automatically align multiple slides, allowing users to:

  • Navigate synchronized sections
  • Compare consecutive sections in real time
 

Master intricate biological geometry with a closed polygon tool designed for instant vertex refinement.

Enhancements to annotation tools include:

  • Closed polygon tool for complex biological structures
  • Vertex editing without requiring full redraw
 

How this improves your workflow: These improvements streamline annotation workflows and improve efficiency.

Multi-Specimen Support

Cases can include:

  • Multiple specimens
  • Multiple slides per specimen

Multi-Report Template Support

A flexible reporting framework allows:

  • Multiple configurable templates within a single deployment
  • Site-specific branding (logos, headers)
  • Customizable fields to meet regulatory requirements

How this improves your workflow: Pathologists can select templates at sign-out, enabling standardized, site-specific reporting across multi-site organizations.

Logically organize your clinical workflow with a refined flow experience

Designed for complex diagnostic environments, the refined flow experience enhances:

  • Traceability
  • Transparency
  • Reproducibility

Key improvements include:

  • Step-level status tracking (completed, rejected, not completed)
  • Transparent audit trails for reruns and corrections

How this improves your workflow: These enhancements reduce user error, clarify workflow logic, and strengthen regulatory readiness and scientific credibility

Search & Navigation

  • Flexible case search using partial matches (name, tags, case ID)
  • Customizable arrow key panning in user profiles

System Monitoring & Configuration

  • Visual diagnostic monitor for identifying infrastructure vs. software bottlenecks
  • Site-wide settings moved to system UI (reducing backend dependency and support needs)
    • Good Clinical Practice (GCP) mode easily toggled on and off

Where can I learn more about HALO AP® 2.5? 

DOCUMENTS 

When can I expect to receive my 2.5 upgrade? 

Indica Labs will be sending out an email to customers soon from info@indicalab.com with instructions on how to submit their upgrade request.

If you haven’t already done so, please add the following emails to your safe sender list to make sure our emails make it to you and not your spam folders: support@indicalab.com, info@indicalab.com, and marketing@indicalab.com.

Once you receive this email and submit your upgrade request, our Technical Solutions team will work with you to schedule your installation.

If you have questions regarding the release, feel free to reach out to support@indicalab.com.

Curious to learn more about an AWS-hosted cloud deployment of HALO AP® with our Cloud Services team? Reach out to support@indicalab.com to learn more about our AWS-validated cloud environment managed by our AWS Certified Solution Architects.

Regulatory

HALO AP® is CE-IVDR marked for in-vitro diagnostic use in Europe, the UK, and Switzerland. HALO AP® is For Research Use Only in the USA and is not FDA cleared for clinical diagnostic use. In addition, HALO AP® provides built-in compliance with FDA 21 CFR Part 11, HIPAA, and GDPR. WBS-MAR-000021v1

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