| Title | Author | Year | Journal |
| Age-related pathology after adenoviral overexpression of the leucine-rich repeat kinase 2 in the mouse striatum | Kritzingerab A, Ferger B, Gillardon F, Stierstorfer B, Birk G, Kochanek S, Ciossek T | 2018 | Neurobiology of Aging |
| Evaluation of PD-L1 expression on vortex-isolated circulating tumor cells in metastatic lung cancer | Dhar M, Wong J, Che J, Matsumoto M, Grogan T, Elashof D, Garon EB, Goldman JW, Christen ES, Carlo DD, Kulkarni RP | 2018 | Scientific Reports |
| Glucagon contibutes to liver zonation | Cheng X, Kim SK, Okamoto H, Xin Y, Yancopoulos GD, Murphy AJ, Gromada J | 2018 | Proceedings of the National Academy of Sciences |
| Ossabaw Pigs With a PCSK9 Gain‐of‐Function Mutation Develop Accelerated Coronary Atherosclerotic Lesions: A Novel Model for Preclinical Studies | Yuan F, Guo L, Park K-H, Woollard JR, Taek‐Geun K, Jiang K, Melkamu T, Zang B, Smith SL, Fahrenkrug SC, Kolodgie FD, Lerman A, Virmani R, Lerman LO, Carlson DF | 2018 | Journal of the American Heart Association |
The neurotrophic tyrosine kinase
receptor TrkA and its ligand NGF
are increased in squamous cell
carcinomas of the lung | Gao F, Griffin N, Faulkner S, Rowe CW, Williams L, Roselli S, Thorne RF, Ferdoush A, Jobling P, Walker MM, Hondermarck H | 2018 | Scientific Reports |
| The novel ATM inhbitior (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan montherapy | Greene J, Nguyen A, Bagby SM, Jones GN, Tai WM, Quackenbush KS, Schreiber A, Messersmith WA, Devaraj KM, Blatchford P, Eckhardt SG, Cadogan EB, Hughes GD, Smith A, Pitts TM, Arcaroli JJ | 2018 | Oncotarget |
| Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs | Li J, Weber E, Guth‐Gundel S, Schuleit M, Kuttler A, Halleux C, Accart N, Doelemeyer A, Basler A, Tigani B, Wuersch K, Fornaro M, Kneissel M, Stafford A, Freedman BR, Mooney DJ | 2018 | Advanced Healthcare Materials |
| Amyloid-β plaques enhance Alzheimer’s brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation | He Z, Guo JL, McBride JD, Narasimhan S, Kim H, Changolkar L, Zhang B, Gathagan RJ, Yue C, Dengler C, Stieber A, Nitla M, Coulter DA, Abel T, Brunden KR, Trojanowski JQ, Lee V M-Y | 2017 | Nature Medicine |
| Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice | Bal NC, Singh S, Reis FCG, Maurya SK, Pani S, Rowland LA, Periasamy M | 2017 | Journal of Biological Chemistry |
| Efficacy of injectable praziquantel for elimination of trematode metacercariae in bluegills (Lepomis macrochirus) and quantification of parasite death by propidium iodide staining | Bader C, Chelladurai JJ, Starling DE, Jones DE, Brewer MT | 2017 | Parasitology Research |
| Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer | Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N | 2017 | Oncotarget |
| Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice | Okamotoa H, Cavinoa K, Na E, Krumm E, Kim SY, Cheng X, Murphy AJ, Yancopoulos GD, Gromada J | 2017 | Proceedings of the National Academy of Sciences |
| Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration | Yousef A, Robinson JL, Irwin DJ, Byrne MD, Kwong LK, Lee EB, Xu Y, Xie SX, Rennert L, Suh ER, Van Deerlin VM, Grossman M, Lee VM-Y, Trojanowski JQ | 2017 | Acta Neuropathologica Communications |
| Neutorphils dominate the immune cell composition in non-small cell lung cancer | Kargl J, Busch SE, Yang GHY, Kim K-H, Hanke ML, Metz HE, Hubbard JJ, Lee SM, Madtes DK, McIntosh MW, Houghton AM | 2017 | Nature Communications |
| Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice | Posgai AL, Wasserfall CH, Kwon K-C, Daniell H, Schatz DA, Atkinson MA | 2017 | Scientific Reports |
| Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations | Guntermann C, Piaia A, Hamel M-L, Theil D, Rubic-Schneider T, del Rio-Espinola A, Dong L, Billich A, Kaupmann K, Dawson J, Hoegenauer K, Orain D, Hintermann S, Stringer R, Pate DD, Doelemeyer A, Deurinck M, and Schümann J | 2017 | JCI Insight |
| Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies | Karpowicz RJ, Haney CM, Mihaila TS, Sandler RM, Petersson EJ, and Lee VM-Y | 2017 | Journal of Biological Chemistry |
| Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring | Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA | 2017 | Environmental Health Perspectives |
| CNS-accessible inhibitor of glucosylceramide synthase for substrate reduction therapy of neuronopathic Gaucher disease | Marshall J, Sun Y, Bangari DS, Budman E, Park H, Nietupski JB, Allaire A, Cromwell MA, Wang B, Grabowski GA, Leonard JP, Cheng SH | 2016 | Molecular Therapy |
| Epigenetic regulation of the thioredoxin-interacting protein (TXNIP) gene by hyperglycemia in kidney | De Marinis Y, Cai M, Bompada P, Atac D, Kotova O, Johansson ME, Garcia-Vaz E, Gomez MF, Laakso M, Groop L | 2016 | Kidney International |
| Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy | Makani V, Zhang B, Han H, Yao Y, Lassalas P, Lou K, Paterson I, Lee VMY, Trojanowski JQ, Ballatore C, Smith AB, Brunden KR | 2016 | Acta Neuropatholgica Communications |
| ProNGF is a potential diagnostic biomarker for thyroid cancer | Faulkner S, Roselli S, Demont Y, Pundavela J, Choquet G, Leissner P, Oldmeadow C, Attia J, Walker MM, Hondermarck H | 2016 | Oncotarget |
| Solid-state NMR structure of a pathogenic fibril of full-length human [alpha]-synuclein | Tuttle MD, Comellas G, Nieuwkoop AJ, Covell DJ, Berthold DA, Kloepper KD, Courtney JM, Kim JK, Barclay AM, Kendall A, Wan W, Stubbs G, Schwieters CD, Lee VMY, George JM, Rienstra CM | 2016 | Structural & Molecular Biology |
| Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma | George D.Yancopoulos, John Rudge, Israel Lowy, Hsin Chieh Lin, Douglas MacDonald, | 2016 | Pigment Cell & Melanoma Research |
| The Dynamics and Turnover of Tau Aggregates in Cultured Cells: Insights into Therapies for Tauopathies | Guo JL, Buist A, Soares A, Callaerts K, Calafate S, Stevenaert F, Daniels JP, Zoll BE, Crowe A, Brunden KR, Moechars D, Lee VMY | 2016 | The Journal of Biological Chemistry |
| Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice | Guo JL, Narasimhan S, Changolkar L, He Z, Stieber Z, Zhang B, Gathagan RJ, Iba M, McBride JD, Trojanowski JQ, Lee VMY | 2016 | Journal of Experimental Medicine |
| Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys | Okamoto H, Kim J, Aglione JP, Lee J, Cavino K, Na E, Rafique A, Kim JH, Harp J, Valenzuela DM, Yancopoulos GD, Murphy AJ, Gromada J | 2015 | Endocrinology |
| Nerve fibers infiltrate the tumor microenvironment and are associated with nerve growth factor production and lymph node invasion in breast cancer | Pundavela J, Roselli S, Faulkner S, Attia J, Scott RJ, Thorne RF, Forbes JF, Bradshaw RA, Walker MM, Jobling P, Hondermarck H | 2015 | Molecular Oncology |
| ANGPTL8/betatrophin does not control pancreatic beta cell expansion | Gusarova V, Alexa CA, Na E, Stevis PE, Xin Y, Bonner-Weir S, Cohen JC, Hobbs HH, Murphy AJ, Yancopoulos GD, Gromada J | 2014 | Cell |
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