Microglial Activation Quantification
The Microglial Activation module measures microglia cell activation in brightfield whole slide images and photomicrographs. This module detects microglia, soma, and processes, and ultimately reports the number of activated microglial cells, the number of inactivated microglial cells, and the number of negative (non-microglia) cells detected. In addition to cell classification and counting, this tool precisely measures cell processes. It reports the total process area and length, as well as the average process area, length, and thickness, and quantifies process branching by counting the number of branch points per cell.
In the example shown above, the microglia are identified in brown and all nuclei are counterstained with hematoxylin. Processes are identified in yellow and the cell bodies of activated microglia are in red and inactive or resting microglia are in green.