4 May 2023 | Indica Labs is pleased to announce our Boston HALO® User Group Meeting at Le Méridien Boston Cambridge on May 4 from 1 pm - 6 pm....
25 May 2023 | Following up on our Masterclass Webinar 1 for Multiplex IHC analysis, Masterclass 2 will discuss advanced workflows to help users tackle more challenging brightfield multiplex IHC assays. First, we will demonstrate how advanced cell segmentation and phenotyping options using HALO AI can be combined with the multiplex IHC module to improve image analysis. Two alternative approaches for analyzing multiplex IHC will also be demonstrated including a serial stain workflow to convert brightfield images into...
11 May 2023 | In this 60-minute webinar, we discuss best practices and optimization techniques for advanced quantitative multiplex immunohistochemical (mIHC) image analysis....
28 March 2023 | Join us for this 1-hour webinar to see a live demonstration of RNAscope image analysis using the HALO® platform from Indica Labs. This webinar will demonstrate the basic functionality of HALO’s RNAscope modules for analysis of brightfield and fluorescence images and will discuss available analysis outputs. In addition, select HALO modules that are commonly used with RNAscope image analysis will be demonstrated, and a brief introduction to how HALO AI can advance your RNAscope will be...
9 February 2023 | A new version of HALO® and HALO AI are coming soon! In this half hour webinar, Donald Allen will discuss and demonstrate new features and functionalities in this software release and end with a Q/A session. ...
2 February 2023 | A new version of HALO® and HALO Link from Indica Labs are coming soon! In this 1-hour webinar, Emily Gamble and Kat Latimer will discuss and demonstrate new features and functionalities in this software release and end with a Q/A session....
21 November 2022 | Join us for this 1-hour webinar to learn how SPIAT can advance your spatial analyses ...
20 October 2022 | Join us for this 1-hour webinar to learn about an iterative chromogenic based Serial Stain workflow in HALO®...
6 October 2022 | Join us for this 1-hour webinar to see a live demonstration of the HALO® image analysis platform, the gold standard analysis platform for quantitative tissue analysis in digital pathology. ...
22 September 2022 | Join us for this 1-hour webinar and learn how MSI and IMC are advancing spatial biology through integration with other imaging and omic analyses...
13 September 2022 | Join us for this 1.5-hour panel discussion on high dimensional clustering to learn about options for performing clustering analysis and for visualizing high dimensional HALO® Highplex FL data, such as UMAP and t-SNE....
29 September 2022 | Join us for this 1-hour webinar for a live demonstration of neurobiology image analysis using HALO® and HALO AI™. Dr. Levi Maston will demonstrate the recently released Microglial Activation modules and the Object Colocalization modules for BF and FL analysis in HALO....
21 July 2022 | A new version of HALO and HALO AI are coming soon! Join this 1-hour webinar presented by Emily Gamble and Donald Allen of the Product Management team who will discuss and demonstrate the new features and functionality of HALO 3.5 and HALO AI 3.5. ...
9 June 2022 | In this 90-minute webinar, Learn about an open-source MIBI image analysis pipeline using HALO data and how to validate a multiplex fluorescence panel for deployment in a clinical setting...
2 June 2022 | In this 60-min webinar, Learn to maximize utility of the HALO Link collaborative image management platform ...
25 May 2022 | In this 60-min webinar, Learn how HALO and HALO AI are advancing neuropathology research at the UW Medicine Biorepository and Integrated Research (BRaIN) laboratory ...
05 May 2022 | In this 60-min webinar, Dr. Ghislaine Lioux will present solutions to common RNAscope image analysis challenges including how to optimize color deconvolution, nuclear segmentation, and how to manage spot clusters...
20 April 2022 | In this 2-hour event, learn from three experts in RNAscope image analysis with HALO® as they present their scientific research, share RNAscope tips and tricks, and participate in a panel discussion. ...
31 March 2022 | In this webinar, Dr. Noemi Kedei, a staff scientist at the Collaborative Protein Technology Resource core of the Center for Cancer Research (CCR) at the National Cancer Institute, will present a comprehensive CODEX workflow, from image acquisition to image processing and HALO image analysis. Dr. Kedei leads the core facility that provides this technology as service to CCR investigators, including project consultation and design, antibody panel customization, tissue staining and imaging, image processing, and...
20 January 2022 | In this 60-minute webinar, learn how HALO and HALO AI collaborate to perform tissue and cell segmentation, quantification of T-cell subsets in tumor regions, and spatial analysis ....
15 December 2021 | This webinar will share an analysis of biomarkers using pre-treatment melanoma samples from the dabrafenib plus trametinib arm of the randomized, Phase III COMBI-v trial using the HALO® image analysis platform combined with gene expression analysis using the Nanostring nCounter technology....
10 December 2021 | In this 1-hour webinar, featured speakers will demonstrate end-to-end how to develop a quantitative assay in HALO and transition it into clinical trials using HALO AP....
03 December 2021 | In this webinar you will learn how the Pharma Services team at Indica Labs uses HALO Link to collaborate with customers, to launch and display image analysis results, and to archive studies...
02 December 2021 | New versions of all of the Indica Labs research products are coming soon! HALO, HALO AI, and HALO Link 3.4 each contain performance and workflow enhancements that the Product Management team is eager to share. In this hour-long webinar, we will discuss and demonstrate these brand-new developments, and end with a Q/A session....
28 October 2021 | The development of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is driven by chronic inflammatory responses and acquired genetic changes. To investigate its genetic bases, we performed targeted sequencing of 93 genes in 131 MALT lymphomas including 76 from the thyroid. We found frequent deleterious mutations of TET2 (86%), CD274 (53%), TNFRSF14 (53%) and TNFAIP3 (30%) in thyroid MALT lymphoma....
21 October 2021 | Gastric cancer is the fourth-leading cause of cancer death worldwide. About 80% of cases are attributable to infection with the bacterium Helicobacter pylori (Hp). Untreated Hp infection causes lifelong stomach inflammation that does not eradicate the bacterium. In some individuals, stomach inflammation leads to preneoplastic progression, a series of sequential tissue changes including loss of gastric acid-producing parietal cells, metaplasia, dysplasia, and finally cancer....
6 October 2021 | CD38, a druggable ectoenzyme, is involved in the generation of adenosine, which is implicated in tumor immune evasion. Its expression and role in prostate tumor-infiltrating immune cells (TIICs) have not been elucidated. We characterized CD38 expression on prostate cancer (PC) epithelial cells and TIICs and explored the association of this expression with clinical outcomes. RNAseq from 159 patients with metastatic castration-resistant prostate cancer (mCRPC) in the International Stand Up To Cancer/Prostate Cancer Foundation (SU2C/PCF) cohort and 171...
8 September 2021 | Digital pathology provides an advantage of automatizing many routine pathological tasks via computational algorithms and tools. The reporting of prostate cases is time-consuming due to a large number of slides per case. Moreover, tumor aggressivity grading (Gleason score) is well known for its subjective nature and high levels of interobserver variability. In this webinar, we will demonstrate a deep learning-based tool developed for the detection of prostate cancer in histological slides (prostate biopsies and prostatectomy...
6 May 2021 | Application Scientist, Natasha Carmell, will discuss and demonstrate workflow approaches for analysing skin sections stained with H&E and immunofluorescence. Using HALO AI we will identify and segment the corneal layer, epidermis, dermis, cartilage, sebaceous glands and lesions in H&E murine auricular tissues, followed by the segmentation of carcinoma from melanoma in fluorescent multiplexed Melanoma tissue. This AI based tissue segmentation will then be combined with biomarker quantification to identify CD8, CD68 and PDL1 positive populations using...
29 April 2021 | Batch processing workflows can be a significant time saver for HALO image analysis. In this masterclass, US Application Scientist Michael Tomac will cover six different batch process workflows available in HALO, including: - Registration, including batch registration of TMAs - Annotation Editing & Deletion - Analysis - Edit Result Layers - Spatial Analysis from scratch and using saved settings - View Settings - Export Michael will also highlight changes in batch workflows introduced in HALO 3.3, so this is a great opportunity for HALO...
22 April 2021 | The upcoming release of HALO and HALO AI contains many exciting improvements that we wanted to share with our users! In this 30 minute webinar, we will announce the new developments within our products and give a live demonstration of the expanded, pathologist-oriented workflows,...
8 April 2021 | The webinar will cover a workflow for performing stain co-localization analysis in sequential IHC cuts through color deconvolution, slide registration, and cell-type classification, including export using registered coordinates. The resulting co-localization output will be compared and contrasted to true co-expression on a single slide using mIF techniques (Polaris)....
1 April 2021 | The Indica Labs software products have a number of additional tools to extend the utility of our products beyond the HALO user interface most users are familiar with. These tools allow users to query the underlying database for metadata imported to HALO Link, integrate with LIMS, plugin convolutional neural networks not available in HALO, write analysis modules from scratch, and more....
4 March 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT Type 1 diabetes is an autoimmune condition leading to the T-cell mediated destruction of insulin-containing beta cells. Worldwide, fewer than 600 Type 1 diabetes pancreata have been described in the literature or are accessible within tissue biobanks. Due to welcome improvements in the diagnosis and clinical management of Type 1 diabetes, deaths close to diagnosis are now very rare in young...
February 2021 | Indica Labs is excited to continue our HALO® Masterclass Webinar Series this winter. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide.These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher...
28 January 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT | Looking for an easy way to quantify plaques or vessels in your images? Register for our next masterclass! In the first of our 2021 Masterclass series, East Coast Application Scientist Alyssa Myers will discuss object-based analysis. Using HALO, this masterclass will provide an in-depth look at our brightfield and fluorescent object colocalization analysis modules....
21 January 2021 8:00 AM – 9:00 AM PST | 11:00 AM - 12:00 PM EST | 4:00 PM - 5:00 PM GMT | As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the...
November 19, 2020 8:00 PST | 11:00 EST | 16:00 GMT As interest in digital pathology continues to grow within the research community we seek to centralize resources in the cloud to offer a collaborative platform with enhanced functionality....
22 October, 2020 8:00 PDT | 11:00 EDT | 16:00 BST Join us for this 30 minute webinar to check out the new features in HALO and HALO AI v3.2. We will give a live demonstration of new features and review improved workflows, including: ...
26 October 2020 11:00 – 12:35 PT As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the disease are critical to guiding treatment and influencing outcomes. Researchers around the world utilized...
Indica Labs is excited to continue our HALO® Masterclass Webinar Series this autumn. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide. These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher training or additional...
15 October 2020, 9:30 PDT | 12:30 EDT | 17:30 BST In this 30 minute presentation, Jeff Dzubay, Ph.D. will present on the following topics: - Immuno-Oncology biomarker assays benefit from high-plex technologies to better understand the immune landscape. - There are multiple workflows for multiplex IHC/IF assays. - HALO® is a comprehensive, easy-to-use, image analysis platform for analyzing multiplex assays to understand the immune profile within the spatial context of the tumor microenvironment. - The Pharma Services group at Indica Labs uses the HALO®...
September 30, 2020 at 8:00 PDT | 11:00 EDT | 16:00 BST Transitioning novel assays underpinned by quantitative image analysis to a clinical environment may seem a daunting task. Whereas research and discovery image analysis workflows are more flexible and open, clinical image analysis assays must be locked down. ...
Webinar | 15 September 2020 7:00 – 9:00 PDT | 10:00 – 12:00 EDT | 15:00 – 17:00 BST In this webinar, you’ll learn about the importance of multiplex biomarker analysis including how advances in multiplexed immunofluorescent imaging and analysis can reveal biological and spatial information....
29 July 2020, 8:00 PDT | 11:00 EDT | 16:00 BST - Biological interactions between functionally distinct immune and tumor cell populations can either promote or inhibit tumor growth. In this 75-minute webinar, we will hear from two research teams who have identified novel prognostic signatures using different spatial analysis and machine learning approaches to measure tumor-immune cell interactions within the tumor immune microenvironment (TIME)....
In lieu of our scheduled onsite user group meetings, Indica Labs is pleased to announce our 2020 US Virtual HALO User Group Meeting. To make participation easier for our US audience, we will break down the user groups into four one-hour webinars over three days starting at 9 AM PDT/12 PM EDT. To get things started each day, Indica Labs' applications & pharma services teams will introduce and demonstrate new features and capabilities that are part of our upcoming HALO 3.1, HALO AI, HALO Link and HALO AP...
In lieu of our scheduled onsite user group meetings, Indica Labs is pleased to announce our 2020 European Virtual HALO User Group Meeting. To make participation more convenient for our European audience, we are breaking the user group into three one-hour webinars over three days, 19-21st May, starting at 11 AM GMT each day. ...
In this free webinar, attendees will learn about how AI-guided technologies can be used to quantify digital pathology images. Presenters will discuss different deployment models for AI in pathology and how to identify projects that will benefit from AI. Four practical-use cases for AI in drug discovery and safety assessment will also be presented....
Indica Labs is excited to introduce our new HALO® Masterclass Webinar Series. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide. These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher training or additional tips...
In lieu of our participation in the now cancelled 2020 AACR Conference, Indica Labs are pleased to bring you webinar presentations from two of our esteemed customers in oncology research and drug discovery, David Krull from GlaxoSmithKline and Dr. David Reiss from Bristol Meyers Squibb, who will present on April 27th and 28th, respectively. Please join us to hear about how Indica Labs image analysis software and pharma services are being used within their organizations to advance oncology drug development....
In lieu of our participation in the now cancelled 2020 AACR Conference, Indica Labs are pleased to bring you webinar presentations from two of our esteemed customers in oncology research and drug discovery, David Krull from GlaxoSmithKline and Dr. David Reiss from Bristol Meyers Squibb, who will present on April 27th and 28th, respectively. Please join us to hear about how Indica Labs image analysis software and pharma services are being used within their organizations to advance oncology drug development....
In this webinar, researchers and pathologists from the University of New Mexico will discuss their recently published study using the HALO AI deep learning convolutional neural network to detect and classify different types of gastric injury. ...
Core laboratories provide a vital service to researchers by offering expert advice on advanced technologies, shared access to specialized instrumentation and software, as well support for specific types of assays. Increasingly, digital slide scanners and quantitative analysis platforms are being centralized into these core labs to give users access to advanced technologies for both fluorescent and brightfield digital pathology....
In this one-hour webinar, we will demonstrate some of the possibilities of the HALO® GraphQL API. The database powering a HALO® or HALO® LinkTM installation stores a wealth of information about image metadata, analysis results, annotations, and more....
Cloud computing has transformed the landscape of computing infrastructure. Many of the most popular websites and applications have embraced this technology to leverage highly available and performant environments while simultaneously controlling costs and adapting to everchanging demand. ...
In this webinar, Dr Anna Martirosyan and Dr. Emmanuel Prestat will introduce the Brightplex platform, including a description of the MDSC Panel, the workflow and techniques employed. A discussion on how the HALO(R) image analysis platform is integrated as an image processing component of the workflow, and how the technology can be applied to investigate the immune contexture of tumors will follow....
In this webinar, Ines Nearchou from the University of St. Andrews will discuss the methodology and the results of the study which were recently published in Cancer Immunology Research. By way of introduction, Dr. Kate Lillard Tunstall, CSO at Indica Labs, will highlight briefly some of the HALO image analysis tools which were used in the study....
By helping scientists make data-driven decisions faster and more efficiently, artificial intelligence (AI) is revolutionizing drug discovery and development. Pathology is no exception and the Pathology Sciences team at AstraZeneca in Cambridge UK is leading the charge. Here, neural networks are being deployed to search digital slides for specific tissue classes, features and pathologies that are not easily quantified using traditional image analysis or are too time-consuming for pathologists to quantify by eye. ...
Leveraging our own image analysis (HALO), AI (HALO AI), and image management (HALO Link) platforms, the Indica Labs’ pharma services team offer a wide range of analysis services to pharmaceutical, contract research organizations and research institutes around the world. ...
With its high spatial heterogeneity and biological complexity, the tumor immune microenvironment presents a characterization challenge for translational researchers. Conventional immunohistochemistry (IHC) methods only provide insight into a limited number of markers of interest. In this 60-minute webinar, Dr. Sean Downing from Ultivue will explain how they are overcoming these limitations and extracting meaningful, highly multiplexed biomarker data from whole slide images using Ultivue’s proprietary multiplexing technology, UltiMapper™ I/O, in combination with the HALO® image analysis platform. ...
In this one hour webinar, Indica Labs’ Application Scientist, Alyssa Myers, will discuss how the HALO platform can be used for quantitative analysis of whole slide images relevant to neuroscience researchers. Following this introduction, Alyssa will give a real-time demonstration of some of our more popular neuroscience-specific modules, including both brightfield and fluorescence examples....
In this webinar, the Ultivue technology and UltiMapper™ I/O kits will be introduced including a fully optimized, automated and optimized staining protocol on the Leica BOND RX platform. Avoiding any linear unmixing after image acquisition, the UltiMapper I/O whole slide images are directly analyzed using the then processed on Indica Labs HALO software, to derive cell counts, marker co-localization and proximity data analyses. HALO therefore provides the analytical tools to tap into convoluted biomarker signatures and answer complex biological questions...
This webinar is a “must see” for anyone interested in PD-1/PD-L1 targeted immunotherapy and quantitative methods for biomarker assessment in immuno-oncology. In this webinar, Dr. Viktor Koelzer from the Institute of Cancer and Genomic Science at the University of Birmingham and the Wellcome Trust Centre for Human Genetics at the University of Oxford will discuss these critical areas of improvement within the context of two recent studies published by the presenter and his colleagues....
In this 60-minute webinar, Indica Labs is pleased to welcome two guest speakers who will discuss how they are using the RNAscope® assay with HALO® quantification software in their institutions. Dr. Gordon Jiang from Beth Israel Deaconess Medical Center | Harvard Medical School will present his original research including the use of chromogenic RNAscope and HALO to analyze PNPLA3 transcirption in Non-Alchoholic Liver Disease (NAFLD). Dr. Julia Jones from Cancer Research UK | Cambridge Institute will explain the RNAscope technology...
