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Automated Detection and Gleason Grading of Prostate Cancer in Digital Pathology

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8 September 2021 | Digital pathology provides an advantage of automatizing many routine pathological tasks via computational algorithms and tools. The reporting of prostate cases is time-consuming due to a large number of slides per case. Moreover, tumor aggressivity grading (Gleason score) is well known for its subjective nature and high levels of interobserver variability. In this webinar, we will demonstrate a deep learning-based tool developed for the detection of prostate cancer in histological slides (prostate biopsies and prostatectomy specimens) and its histological grading (Gleason grading). We will present the results of the actual validation study showing high levels of accuracy in both tasks. We will discuss the practical aspects of the implementation of such tools in the diagnostic routine.

Automated Detection and Gleason Grading of Prostate Cancer in Digital Pathology Read More »

Automated detection and classification of prognostic histopathological features in colorectal cancer using deep learning

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9 June 2021 | Deep learning can be applied to both clinical and research based digital pathology. Doing so can bring multiple advantages to both fields. In this talk, Dr. Peter Caie and Dr. Ines Nearchou we will discuss these advantages and describe a specific proof of principle that applies AI to the quantification of an important histopathological feature in colorectal cancer, desmoplastic reaction (DR).

Automated detection and classification of prognostic histopathological features in colorectal cancer using deep learning Read More »

Approaches to Analyzing Skin Tissue using HALO and HALO AI

Area Quantification, Events, HALO, HALO AI, HALO Modules, Highplex FL, News, Past Webinars, Spatial Analysis, Webinars / , , , , ,

6 May 2021 | Application Scientist, Natasha Carmell, will discuss and demonstrate workflow approaches for analysing skin sections stained with H&E and immunofluorescence. Using HALO AI we will identify and segment the corneal layer, epidermis, dermis, cartilage, sebaceous glands and lesions in H&E murine auricular tissues, followed by the segmentation of carcinoma from melanoma in fluorescent multiplexed Melanoma tissue. This AI based tissue segmentation will then be combined with biomarker quantification to identify CD8, CD68 and PDL1 positive populations using Highplex FL.

Approaches to Analyzing Skin Tissue using HALO and HALO AI Read More »

Comparison of stain co-localization in IHC sequential cuts and true co-expression in mIF images from Polaris

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8 April 2021 | The webinar will cover a workflow for performing stain co-localization analysis in sequential IHC cuts through color deconvolution, slide registration, and cell-type classification, including export using registered coordinates. The resulting co-localization output will be compared and contrasted to true co-expression on a single slide using mIF techniques (Polaris).

Comparison of stain co-localization in IHC sequential cuts and true co-expression in mIF images from Polaris Read More »

HALO Image Analysis Masterclass Series: Indica Labs Tech Toolbox Webinar

Events, GraphQL API, HALO, HALO AI, HALO AP, HALO Link, Masterclasses, News, Past Webinars, Webinars / , , , ,

1 April 2021 | The Indica Labs software products have a number of additional tools to extend the utility of our products beyond the HALO user interface most users are familiar with. These tools allow users to query the underlying database for metadata imported to HALO Link, integrate with LIMS, plugin convolutional neural networks not available in HALO, write analysis modules from scratch, and more.

HALO Image Analysis Masterclass Series: Indica Labs Tech Toolbox Webinar Read More »

Webinar: Using the HALO image analysis platform to study pancreas pathology and insulitis in young people with recent-onset Type 1 diabetes

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4 March 2021 | 8:00 AM – 9:00 AM PST | 11:00 AM – 12:00 PM EST | 4:00 PM – 5:00 PM GMT
Type 1 diabetes is an autoimmune condition leading to the T-cell mediated destruction of insulin-containing beta cells. Worldwide, fewer than 600 Type 1 diabetes pancreata have been described in the literature or are accessible within tissue biobanks. Due to welcome improvements in the diagnosis and clinical management of Type 1 diabetes, deaths close to diagnosis are now very rare in young children, highlighting the value and importance of these archival samples.

Webinar: Using the HALO image analysis platform to study pancreas pathology and insulitis in young people with recent-onset Type 1 diabetes Read More »

HALO Image Analysis Masterclass Series: February-March 2021

Events, FISH-IF, HALO, HALO AI, HALO Modules, Highplex FL, ISH module, ISH-IHC module, Islet IHC module, Masterclasses, News, Past Webinars, Tissue Classifier, Webinars / , , , , , , , ,

Spring of 2021 | Indica Labs is excited to continue our HALO® Masterclass Webinar Series this winter. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide.These webinars are suitable for prospective customers who want to see a more in depth demonstration as well as current users looking for refresher training or additional tips and tricks.Registration is required for each webinar and participation will be limited, so early registration is encouraged.

HALO Image Analysis Masterclass Series: February-March 2021 Read More »

Webinar | HALO® Image Analysis Masterclass Series: Object-based Analysis

Events, HALO, HALO Modules, Masterclasses, News, Object Colocalzation FL, Object Colocalzation module, Past Webinars, Spatial Analysis, Webinars / , , , ,

28 January 2021 | 8:00 AM – 9:00 AM PST | 11:00 AM – 12:00 PM EST | 4:00 PM – 5:00 PM GMT | Looking for an easy way to quantify plaques or vessels in your images? Register for our next masterclass! In the first of our 2021 Masterclass series, East Coast Application Scientist Alyssa Myers will discuss object-based analysis. Using HALO, this masterclass will provide an in-depth look at our brightfield and fluorescent object colocalization analysis modules.

Webinar | HALO® Image Analysis Masterclass Series: Object-based Analysis Read More »

Webinar | Digital Pathology in the New Normal: Leveraging HALO® to Investigate a Global Pandemic

Area Quantification, Events, HALO, HALO AI, HALO Modules, Highplex FL, ISH-IHC module, Multiplex IHC, News, Past Webinars, Serial Section Analysis, Spatial Analysis, Webinars / , , , , , , , ,

21 January 2021 | 8:00 AM – 9:00 AM PST | 11:00 AM – 12:00 PM EST | 4:00 PM – 5:00 PM GMT |
As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the disease are critical to guiding treatment and influencing outcomes. Researchers around the world utilized the HALO suite of products to share rare digital pathology slides, collect quantitative pathological data from translational models, characterize gene expression in immune response, and integrate transcriptional data with tissue-based immunoprofiling. This workshop will present some insight on how HALO has been used by researchers at 3 different global institutions to study and characterize COVID-19.

Webinar | Digital Pathology in the New Normal: Leveraging HALO® to Investigate a Global Pandemic Read More »

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