Getting Started with Multiplex Fluorescence Image Analysis in HALO®
11 June 2025 | Learn the basics of multiplex fluorescence image analysis!
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Highplex FL
Unlocking Deeper Insights with the HALO® High Dimensional Analysis Module
Extracting biological insights from highly multiplexed data requires both powerful image analysis tools and intuitive methods to navigate high-dimensional data. In this blog, we’ll cover the basics of dimensionality reduction and unsupervised clustering and explore our new High Dimensional Analysis module.
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Indica Labs Announces Launch of High Dimensional Analysis Module for the HALO® Image Analysis Platform
Albuquerque, NM, 8 April 2025 – Indica Labs today announces the launch of the High Dimensional Analysis module for the HALO® image analysis platform. This exciting new functionality for customers in the life sciences enables advanced phenotypic characterization and spatial analysis as well as the exploration of highly multiplexed datasets in either brightfield or fluorescence.
SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence
SARS-CoV-2, the causative agent of COVID-19, has been the focus of intense research since its detection in late 2019. It is known that viral infection
Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy
Stereotactic body radiotherapy (SBRT) uses multiple targeted beams of radiation to damage malignant cells while limiting effects to surrounding tissue. SBRT is a standard treatment
Highplex FL
Quantify expression of an unlimited number of biomarkers in any cellular compartment – membrane, nucleus or cytoplasm.
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
Jason Yongsheng Chan,et al, The Journal of Clinical Investigation, 2020.
To molecularly characterize the rare and aggressive tumors known as angiosarcomas, Chan et al utilized a combination of transcriptomic immuno-oncology profiling with multiplex immunohistochemistry and immunofluorescence. HALO image analysis software was used for the quantification of PD-L1, CD68, CD8, FOXP3, CD15, and ERG. From these studies, three phenotypes of patients were identified according to etiology, anatomical origin, signaling pathways, and the tumor inflammation signature. These distinct biological phenotypes provide opportunity for future studies to improve prognosis and treatment of a rare and deadly disease.
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Virtual US User Group Meeting Presentation: A Digital Pathology Repository for COVID, An Evolving Need
8-11 June 2020 | In lieu of our scheduled onsite user group meetings, Indica Labs is pleased to announce our 2020 US Virtual HALO User Group Meeting. To make participation easier for our US audience, we will break down the user groups into four one-hour webinars over three days starting at 9 AM PDT/12 PM EDT.
Brightplex: Combining the power of multiplexing & the ease of chromogenic IHC to assess complex immune phenotypes in the TME
11 June 2019 | In this webinar, Dr Anna Martirosyan and Dr. Emmanuel Prestat will introduce the Brightplex platform, including a description of the MDSC Panel, the workflow and techniques employed. A discussion on how the HALO(R) image analysis platform is integrated as an image processing component of the workflow, and how the technology can be applied to investigate the immune contexture of tumors will follow.