Pathology
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With the HALO® Image Analysis Platform, the gold standard analysis solution for digital pathology
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Explore Our Solutions

Backed by cutting edge technology, an uncompromising focus on ease-of-use and dedicated customer service, Indica Labs’ software and services are being used to make vital discoveries in pathology labs and research organizations around the world. Discover how our solutions can help you.

HALO® Image Analysis

With uncompromising ease-of-use and flexibility, the HALO® Image Analysis Platform can adapt to any image analysis application.

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HALO AI Deep Learning

HALO AI, the first of its kind intuitive interface for deep learning in digital pathology, is putting the power of AI in the hands of the pathologist.

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HALO Link Image Management

Share images and analysis data with remote collaborators using HALO Link, our browser-based image management system.

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Pharma Services

If you are overwhelmed with your image analysis workload or need help with more complex analysis, our Pharma Services team can help.

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HALO AP Clinical Workflow

The HALO AP® platform brings case-centric automation, collaboration and quantification to your Anatomic Pathology lab.

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Explore Our Integrated Platforms

Click play to learn how all of our HALO products fit together to offer an end-to-end Digital Pathology workflow from bench to bedside!

 
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Read What Our Customers Are Publishing

Our customers are making vital discoveries in oncology, neuroscience, infectious disease, and diabetes research. Check out some of the research our customers are publishing using the HALO Image Analysis Platform and Indica analysis modules.

Check out some of the research our customers are publishing using the HALO Image Analysis Platform and Indica analysis modules.

SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence

SARS-CoV-2, the causative agent of COVID-19, has been the focus of intense research since its detection in late 2019. It is known that viral infection affects several cellular processes, including senescence and inflammation, and prior studies also point toward SARS-CoV-2...

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Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

Schwannomas are sporadic, usually benign tumors that develop predominately on spinal nerve roots and cranial nerves. Inactivation of NF2 in Schwann cells (SC) is the cause of nearly all schwannomas and mutations in additional genes are few if present at...

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High Impact Publications with the HALO® Image Analysis Platform

Browse this selection of high-impact publications to learn how HALO image analysis is leveraged in fields from immuno-oncology to neuroscience and infectious disease.

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RNAscope® Publications with the HALO® Image Analysis Platform

Read this publications list to see examples of research in areas from neuroscience to oncology using HALO to analyze RNAscope images.

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Indica Labs, Inc. will use the information you provide on this form to provide updates and marketing, including but not limited to, webinars, events, and software releases. We will treat your information with respect. You can unsubscribe from our emails at any time. For more information about our privacy practices please read our Privacy Policy.
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Check out some of the research our customers are publishing using the HALO AI Deep Learning Classifier Add-on.

Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patients with non-small cell lung cancer

Predictive biomarkers to determine which non small cell lung cancer (NSCLC) patients will respond to immunotherapy are currently lacking. In this Nature Cancer publication, the authors combine computed tomography imaging, PD-L1 immunohistochemistry (IHC), and genomic data to predict responses to...

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Prognostic Value of CD8+ Lymphocytes in Hepatocellular Carcinoma and Perineoplastic Parenchyma Assessed by Interface Density Profiles in Liver Resection Samples

This study examined CD8+ cell distribution in hepatocellular carcinoma (HCC) and peritumoral liver tissue to investigate the overall survival (OS) and recurrence-free survival (RFS). It is well understood that CD8+ lymphocytes are involved in both the anti-tumor response and in...

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HALO AI High Impact Publications

Review this selection of high-impact publications for examples of HALO AI applications in fields ranging from metabolism to immuno-oncology and myology.

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Indica Labs, Inc. will use the information you provide on this form to provide updates and marketing, including but not limited to, webinars, events, and software releases. We will treat your information with respect. You can unsubscribe from our emails at any time. For more information about our privacy practices please read our Privacy Policy.
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Check out some of the research our customers are publishing using the HALO Link Image Management Platform.

Clinical, histopathological and molecular features of dedifferentiated melanomas: An EORTC Melanoma Group Retrospective Analysis

Melanoma, a highly aggressive type of skin cancer originating from pigment-producing cells called melanocytes, can be a source of diagnostic confusion for pathologists. While primary melanomas are easily recognizable, metastatic melanomas can dedifferentiate and exhibit varied and misleading cyto-architectural characteristics,...

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Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer

High-grade serous ovarian cancer (HGSC) is known to have a high degree of both genetic and immunologic heterogeneity, can be resistant to chemotherapy, and commonly recurs in patients. It is also the most common form of ovarian cancer and represents...

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Customer Reviews

Read independent SelectScience reviews on HALO® and learn how these customers are using Indica Labs’ solutions to streamline their workflows.

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HALO is the simply the best whole-slide analysis software available.

"HALO is simply the best whole-slide analysis software available. We have a large core facility, scanning over 15,000 brightfield and 2,000 fluorescence slides per year (plus many confocal microscopes, etc.). For whole-slide analysis, we formerly used Genie (from Aperio), and InForm (from Perkin Elmer), and we have collaborators using Definiens (no longer available) and Visiopharm. But now we have over 50 users per month working on HALO and the other platforms have been virtually shut down. HALO is very easy to get up and running - within a 2 hour session we can get a new user started with their own classification and cell counting application. Most users run a batch analysis overnight and collect and review their results in the morning. The team at Indica Labs are quick to respond when we have a challenging analysis project - they will WebEx in and help optimize the parameters. They have the experience (and courage) to tell us if the staining is just not suitable or a more complex classifier is required."

 

James Jonkman

University Health Network, Advanced Optical Microscopy Facility

Excellent tool, fast, user friendly, powerful.

"I am almost completely satisfied with the HALO image analysis platform. The main areas of improvement would be in cell segmentation using membrane markers and in data analysis after datafication of the slide. My principle bottleneck is in creating actionable insight from the multiple reported parameters. I think that Indica's experience with AI and multiplex data generation positions you well to exploit the current need in the marketplace. One more thing - phenotyping manually by thresholding with no morphology/cell size, neighbor information is good but if I had a magic wand, then phenotyping would be a full suite of tools with spatial, multimarker, and morphological features that could be weighted from 0 to 1 in a machine learning classifier model."

Michael Surace

AstraZeneca

For the Pathologist, HALO is by far the best digital image analysis platform available.

"As a Pathologist specializing in digital image analysis, I have had the opportunity to use several different digital image analysis platforms. Indica Labs' HALO is by far the most accurate, versatile and user friendly digital image analysis platform that I have used. Literally within 10-15 minutes of "tuning" one of their "out of the box" detection algorithms, I can perform image analysis for most simple immunohistochemical markers. The workflow is simple, with sacanned images being imported directly into HALO with or without annotations for analysis. This even allows for remote use when working off site. The customer support is AMAZING and I routinely get same day or next day help from the technical support reps. HALO is a must have for any pathologist or scientist involved in quantifying immunohistochemical stains. In addition the HALO AI module is extremely easy to use. Within 20 minutes I was able to set up AI detection of tumor vs. normal tissue, as well as tumor epithelium vs. stroma. HALO provides everything one needs for quantification of IHC for clinical and pre-clinical studies (of course with supervision of a pathologist). Best of all: it is fun, like a video game for Pathologists! "

Philip Martin

AstraZeneca

We use HALO & HALO-Link daily to coordinate studies for our analysts and pathologists.

"HALO is a whole-slide image analysis platform that is designed to work how pathologists classify & score images using a microscope. It uses a set of tools that are very familiar to anyone who has used any type of image viewing/editing program at home. It can be learned in a day to analyze brightfield & fluorescent whole slide images and TMAs. There are sophisticated tools to analyze tissues labeled by chromogenic and fluorescent IHC, RNAScope, FISH & ISH. HALO may be installed on stand-alone workstations or cloud services such as AWS. File sharing through HALO-Link lets user access studies through a simple web-interface sharing a common database. HALO AI allows any user to developing sophisticated AI based tissue classification without the need for external programs or expensive computing hardware."

Timothy Baradet

Bristol-Myers Squibb

Amazing software and service.

"Indica labs is of great support when using HALO. Their customer service is really great. HALO is a very user friendly software, but the technical support is also what makes it the best digital pathology software on the market. they are always open to any suggestion and the response time is usually very short."

Camille Britton-Rivet

Immunocore

Highly recommend.

"I work mostly with multiplex immunohistochemistry images evaluating the tumor microenvironment with a focus on tumor infiltration and cell-cell interactions. I've used several image analysis softwares over the years, but I continue to use HALO because it is easy to use yet very powerful. I started using HALO back when Indica Labs was a much smaller company and before they launched HALO Link (which I also like). Although they've grown substantially, they continue to try to provide great customer service and are always working to improve their product. No technology is perfect, but they appear to be passionate about getting past the hurdles of image analysis and to expand the functionality of the software while keeping the learning curve reasonable. I put 4/5 for Ease of Use due more to some functionality improvements that are needed."

Kimberly Smythe

Fred Hutch Cancer Center

Latest News & Events

Catch up on the latest blogs, press releases, event announcements and other news at Indica Labs.

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Clinical, histopathological and molecular features of dedifferentiated melanomas: An EORTC Melanoma Group Retrospective Analysis

Melanoma, a highly aggressive type of skin cancer originating from pigment-producing cells called melanocytes, can be a source of diagnostic confusion for pathologists. While primary melanomas are easily recognizable, metastatic melanomas can dedifferentiate and exhibit varied and misleading cyto-architectural characteristics,...

Learn More
Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer

High-grade serous ovarian cancer (HGSC) is known to have a high degree of both genetic and immunologic heterogeneity, can be resistant to chemotherapy, and commonly recurs in patients. It is also the most common form of ovarian cancer and represents...

Learn More
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