Calcium/calmodulin-stimulated protein kinase II (CaMKII) is a multi-functional kinase that controls a range of cellular functions, including proliferation, differentiation and apoptosis. The biological properties of
BRAF inhibitors are highly effective therapies for the treatment of BRAFV600-mutated melanoma, with the main toxicity being a variety ofhyperproliferative skin conditions due to paradoxical activation of
Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors Read More »
Indica Labs’ Sales Application Scientist Adam Smith will be presenting on the STRATA Platform July 14th from 11:45-12:15 at the 2nd Digital Pathology Congress in
Join Indica Labs at the 2nd Digital Pathology Congress in Philadelphia Read More »
Indica Labs would like to formally invite you to the Inaugural East Coast HALOTM User Group Meeting which will be held on 11th February, 2016
Inaugural East Coast HALO User Group to be held in Cambridge, MA on February 11, 2016 Read More »
Discoveries from the field: Expediting drug developments and clinical trials with digital pathology and HALO image analysis Alex Klimowicz, PhD, Principal Scientist, Boehringer Ingelheim Pharmaceuticals
File Formats: Non-proprietary (JPG, TIF, OME.TIFF) Nikon (ND2) 3DHistech (MRXS) Akoya (QPTIFF, component TIFF) Olympus / Evident (VSI) Hamamatsu (NDPI, NDPIS) Aperio (SVS, AFI) Zeiss
Supported File Formats for HALO®, HALO AI, and HALO Link Read More »
The TNF-α-induced protein 8 (TNFAIP8 or TIPE) is a risk factor for cancer and bacterial infection, and its expression is upregulated in a number of
Exacerbated Experimental Colitis in TNFAIP8-Deficient Mice Read More »
Infiltration of the tumor microenvironment by nerve fibers is an understudied aspect of breast carcinogenesis. In this study, the presence of nerve fibers was investigated
Recently, it was reported that angiopoietin-like protein 8 (ANGPTL8) was the long-sought “betatrophin” that could control pancreatic beta cell proliferation. However, studies of Angptl8(?/?) mice
ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion Read More »
Islet-1 (Isl-1) is essential for the survival and ensuing differentiation of pancreatic endocrine progenitors. Isl-1 remains expressed in all adult pancreatic endocrine lineages; however, its
Islet-1 is essential for pancreatic beta cell function Read More »
