HALO

Brightplex: Combining the power of multiplexing & the ease of chromogenic IHC to assess complex immune phenotypes in the TME

11 June 2019 | In this webinar, Dr Anna Martirosyan and Dr. Emmanuel Prestat will introduce the Brightplex platform, including a description of the MDSC Panel, the workflow and techniques employed. A discussion on how the HALO(R) image analysis platform is integrated as an image processing component of the workflow, and how the technology can be applied to investigate the immune contexture of tumors will follow.

Brightplex: Combining the power of multiplexing & the ease of chromogenic IHC to assess complex immune phenotypes in the TME Read More »

Combined analysis of tumor buds, lymphocytic infiltration and their spatial relationship within the tumor microenvironment improves prognostic accuracy colorectal cancer

29 May 2020 | In this webinar, Ines Nearchou from the University of St. Andrews will discuss the methodology and the results of the study which were recently published in Cancer Immunology Research.  By way of introduction, Dr. Kate Lillard Tunstall, CSO at Indica Labs, will highlight briefly some of the HALO image analysis tools which were used in the study.

Combined analysis of tumor buds, lymphocytic infiltration and their spatial relationship within the tumor microenvironment improves prognostic accuracy colorectal cancer Read More »

Integration of Artificial Intelligence with Digital Pathology: Deployment Considerations & Cases Studies in Pharma

24 April 2019 | By helping scientists make data-driven decisions faster and more efficiently, artificial intelligence (AI) is revolutionizing drug discovery and development.  Pathology is no exception and the Pathology Sciences team at AstraZeneca in Cambridge UK is leading the charge.  Here, neural networks are being deployed to search digital slides for specific tissue classes, features and pathologies that are not easily quantified using traditional image analysis or are too time-consuming for pathologists to quantify by eye.

Integration of Artificial Intelligence with Digital Pathology: Deployment Considerations & Cases Studies in Pharma Read More »

Transforming tissue-based translational research with advanced multiplexing technologies, image analysis and cloud collaboration

25 October 2018 | With its high spatial heterogeneity and biological complexity, the tumor immune microenvironment presents a characterization challenge for translational researchers. Conventional immunohistochemistry (IHC) methods only provide insight into a limited number of markers of interest. In this 60-minute webinar, Dr. Sean Downing from Ultivue will explain how they are overcoming these limitations and extracting meaningful, highly multiplexed biomarker data from whole slide images using Ultivue’s proprietary multiplexing technology, UltiMapper™ I/O, in combination with the HALO® image analysis platform. He will describe how Ultivue’s technology works with existing stains and scanners, and finally, how Ultivue utilizes HALO LINK™ as its digital image management tool to facilitate remote access to biomarker data and secure file sharing with its customers across the world.

Transforming tissue-based translational research with advanced multiplexing technologies, image analysis and cloud collaboration Read More »

HALO® Analysis Applications in Neuroscience Research

15 August 2018 | In this one hour webinar, Indica Labs’ Application Scientist, Alyssa Myers, will discuss how the HALO platform can be used for quantitative analysis of whole slide images relevant to neuroscience researchers. Following this introduction, Alyssa will give a real-time demonstration of some of our more popular neuroscience-specific modules, including both brightfield and fluorescence examples.

HALO® Analysis Applications in Neuroscience Research Read More »

Ultivue Webinar Features HALO Image Analysis: End-to-End Application of UltiMapper Kits for Multiplexed Immuno-Profiling in FFPE Tumor Samples

18 July 2018 | In this webinar,  the Ultivue technology and UltiMapper™ I/O kits will be introduced including a fully optimized, automated and optimized staining protocol on the Leica BOND RX platform.  Avoiding any linear unmixing after image acquisition, the UltiMapper I/O whole slide images are directly analyzed using the then processed on Indica Labs HALO software, to derive cell counts, marker co-localization and proximity data analyses. HALO therefore provides the analytical tools to tap into convoluted biomarker signatures and answer complex biological questions posed by the tumor micro-environment.

Ultivue Webinar Features HALO Image Analysis: End-to-End Application of UltiMapper Kits for Multiplexed Immuno-Profiling in FFPE Tumor Samples Read More »

Computational pathology: A new platform to empower personalized immunotherapy

12 July 2018 | This webinar is a “must see” for anyone interested in PD-1/PD-L1 targeted immunotherapy and quantitative methods for biomarker assessment in immuno-oncology. In this webinar, Dr. Viktor Koelzer from the Institute of Cancer and Genomic Science at the University of Birmingham and the Wellcome Trust Centre for Human Genetics at the University of Oxford will discuss these critical areas of improvement within the context of two recent studies published by the presenter and his colleagues.

Computational pathology: A new platform to empower personalized immunotherapy Read More »

RNAscope ISH Quantification using the HALO® Image Analysis Platform

21 June 2018 | In this 60-minute webinar, Indica Labs is pleased to welcome two guest speakers who will discuss how they are using the RNAscope assay with HALO® quantification software in their institutions. Dr. Gordon Jiang from Beth Israel Deaconess Medical Center | Harvard Medical School will present his original research including the use of chromogenic RNAscope and HALO to analyze PNPLA3 transcirption in Non-Alchoholic Liver Disease (NAFLD). Dr. Julia Jones from Cancer Research UK | Cambridge Institute will explain the RNAscope technology in more depth and give examples of how the histopathology/ISH core facility utilizes HALO for quantification of single/dual chromogenic and multiplexed fluorescent RNAscope probes to answer research questions posed by investigators within the institute. Full abstracts for individual presentations can be found below.

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