Multiplex IHC

Webinar | Digital Pathology in the New Normal: Leveraging HALO® to Investigate a Global Pandemic

Area Quantification, Events, HALO, HALO AI, HALO Modules, Highplex FL, ISH-IHC, Multiplex IHC, News, Past Webinars, Serial Section Analysis, Spatial Analysis, Webinars / , , , , , , , , , , ,

21 January 2021 | 8:00 AM – 9:00 AM PST | 11:00 AM – 12:00 PM EST | 4:00 PM – 5:00 PM GMT |
As the world was shutting down in the face of the COVID-19 pandemic, Digital Pathology was thrust to the forefront as a vital option for not only completing existing projects, but more importantly in understanding the disease of COVID-19. Characterizing the mechanisms by which the novel coronavirus attacks the human body, and also understanding the immune system’s response to the disease are critical to guiding treatment and influencing outcomes. Researchers around the world utilized the HALO suite of products to share rare digital pathology slides, collect quantitative pathological data from translational models, characterize gene expression in immune response, and integrate transcriptional data with tissue-based immunoprofiling. This workshop will present some insight on how HALO has been used by researchers at 3 different global institutions to study and characterize COVID-19.

Webinar | Digital Pathology in the New Normal: Leveraging HALO® to Investigate a Global Pandemic Read More »

Virtual US User Group Meeting Presentation: A Digital Pathology Repository for COVID, An Evolving Need

Events, HALO, HALO AI, HALO AP, HALO Link, HALO Modules, Highplex FL, Multiplex IHC, News, Past Webinars, Past Workshops, Spatial Analysis, Tissue Classifier, Webinars / , , , , , , , , , ,

8-11 June 2020 | In lieu of our scheduled onsite user group meetings, Indica Labs is pleased to announce our 2020 US Virtual HALO User Group Meeting.  To make participation easier for our US audience, we will break down the user groups into four one-hour webinars over three days starting at 9 AM PDT/12 PM EDT.

Virtual US User Group Meeting Presentation: A Digital Pathology Repository for COVID, An Evolving Need Read More »

HALO® IMAGE ANALYSIS MASTERCLASS WEBINAR SERIES 2020

Events, FISH, FISH-IF, HALO, HALO AI, HALO Modules, Highplex FL, ISH, ISH-IHC, Masterclasses, Multiplex IHC, News, Past Webinars, Serial Section Analysis, Spatial Analysis, TMA, Webinars / , , , , , , , , , , , , , , , , , ,

Summer of 2020 Indica Labs is excited to introduce our new HALO® Masterclass Webinar Series. Each masterclass webinar will offer a deep dive into a specific module or capability within our HALO, HALO AI, HALO Link or HALO AP platforms, presented by our expert team of application scientists who train and support our customer base worldwide.

HALO® IMAGE ANALYSIS MASTERCLASS WEBINAR SERIES 2020 Read More »

Spatial Organization of Immune Cells in the Pancreatic Ductal Adenocarcinoma (PDAC) Tumor Microenvironment

Events, HALO, HALO Modules, Multiplex IHC, News, Past Webinars, Serial Section Analysis, Tissue Classifier, Webinars / , , , ,

28 April 2020 | In lieu of our participation in the now cancelled 2020 AACR Conference, Indica Labs are pleased to bring you webinar presentations from two of our esteemed customers in oncology research and drug discovery, David Krull from GlaxoSmithKline and Dr. David Reiss from Bristol Meyers Squibb, who will present on April 27th and 28th, respectively.   Please join us to hear about how Indica Labs image analysis software and pharma services are being used within their organizations to advance oncology drug development.

Spatial Organization of Immune Cells in the Pancreatic Ductal Adenocarcinoma (PDAC) Tumor Microenvironment Read More »

Digital image analysis improves precision of PD‐L1 scoring in cutaneous melanoma

HALO Publications, Multiplex IHC, Publications /

Viktor H. Koelzer, et al, Nature Medicine, 2018. Immune checkpoint inhibitors have become a successful treatment in metastatic melanoma. The high response rates in a subset of patients suggest that a sensitive companion diagnostic test is required. The predictive value of programmed death ligand 1 (PD‐L1) staining in melanoma has been questioned due to inconsistent correlation with clinical outcome. Whether this is due to predictive irrelevance of PD‐L1 expression or inaccurate assessment techniques remains unclear. The aim of this study was to develop a standardised digital protocol for the assessment of PD‐L1 staining in melanoma and to compare the output data and reproducibility to conventional assessment by expert pathologists.

Digital image analysis improves precision of PD‐L1 scoring in cutaneous melanoma Read More »

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

Publications /

Evidence from mouse chronic viral infection models suggests that CD8+T cell subsets characterized by distinct expression levels of the receptor PD-1 diverge in their state

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade Read More »

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

Publications /

Abstract We conducted a first-in-human study of intravenous delivery of a single dose of autologous T cells redirected to the epidermal growth factor receptor variant

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma Read More »

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