HALO Modules

Combined analysis of tumor buds, lymphocytic infiltration and their spatial relationship within the tumor microenvironment improves prognostic accuracy colorectal cancer

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29 May 2020 | In this webinar, Ines Nearchou from the University of St. Andrews will discuss the methodology and the results of the study which were recently published in Cancer Immunology Research.  By way of introduction, Dr. Kate Lillard Tunstall, CSO at Indica Labs, will highlight briefly some of the HALO image analysis tools which were used in the study.

Combined analysis of tumor buds, lymphocytic infiltration and their spatial relationship within the tumor microenvironment improves prognostic accuracy colorectal cancer Read More »

Transforming tissue-based translational research with advanced multiplexing technologies, image analysis and cloud collaboration

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25 October 2018 | With its high spatial heterogeneity and biological complexity, the tumor immune microenvironment presents a characterization challenge for translational researchers. Conventional immunohistochemistry (IHC) methods only provide insight into a limited number of markers of interest. In this 60-minute webinar, Dr. Sean Downing from Ultivue will explain how they are overcoming these limitations and extracting meaningful, highly multiplexed biomarker data from whole slide images using Ultivue’s proprietary multiplexing technology, UltiMapper™ I/O, in combination with the HALO® image analysis platform. He will describe how Ultivue’s technology works with existing stains and scanners, and finally, how Ultivue utilizes HALO LINK™ as its digital image management tool to facilitate remote access to biomarker data and secure file sharing with its customers across the world.

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HALO® Analysis Applications in Neuroscience Research

Area Quantification, Axon Quantification module, Branch Structure FL, Branch Structure module, Events, FISH, HALO, HALO Modules, Microglial Activation module, News, Object Colocalzation FL, Object Colocalzation module, Past Webinars, Tissue Classifier, Webinars / , , , , , , , , , ,

15 August 2018 | In this one hour webinar, Indica Labs’ Application Scientist, Alyssa Myers, will discuss how the HALO platform can be used for quantitative analysis of whole slide images relevant to neuroscience researchers. Following this introduction, Alyssa will give a real-time demonstration of some of our more popular neuroscience-specific modules, including both brightfield and fluorescence examples.

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Ultivue Webinar Features HALO Image Analysis: End-to-End Application of UltiMapper Kits for Multiplexed Immuno-Profiling in FFPE Tumor Samples

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18 July 2018 | In this webinar,  the Ultivue technology and UltiMapper™ I/O kits will be introduced including a fully optimized, automated and optimized staining protocol on the Leica BOND RX platform.  Avoiding any linear unmixing after image acquisition, the UltiMapper I/O whole slide images are directly analyzed using the then processed on Indica Labs HALO software, to derive cell counts, marker co-localization and proximity data analyses. HALO therefore provides the analytical tools to tap into convoluted biomarker signatures and answer complex biological questions posed by the tumor micro-environment.

Ultivue Webinar Features HALO Image Analysis: End-to-End Application of UltiMapper Kits for Multiplexed Immuno-Profiling in FFPE Tumor Samples Read More »

RNAscope ISH Quantification using the HALO® Image Analysis Platform

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21 June 2018 | In this 60-minute webinar, Indica Labs is pleased to welcome two guest speakers who will discuss how they are using the RNAscope assay with HALO® quantification software in their institutions. Dr. Gordon Jiang from Beth Israel Deaconess Medical Center | Harvard Medical School will present his original research including the use of chromogenic RNAscope and HALO to analyze PNPLA3 transcirption in Non-Alchoholic Liver Disease (NAFLD). Dr. Julia Jones from Cancer Research UK | Cambridge Institute will explain the RNAscope technology in more depth and give examples of how the histopathology/ISH core facility utilizes HALO for quantification of single/dual chromogenic and multiplexed fluorescent RNAscope probes to answer research questions posed by investigators within the institute. Full abstracts for individual presentations can be found below.

RNAscope ISH Quantification using the HALO® Image Analysis Platform Read More »

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